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A comparative study on the antibacterial photodynamic efficiency of a curcumin derivative and a formulation on a porcine skin model

Tortik, Nicole ; Steinbacher, Peter ; Maisch, Tim ; Spaeth, Andreas ; Plaetzer, Kristjan


Introduction: The propagation of pathogens resistant to antibiotics around the globe has induced an urgent call for action: alternatives to conventional antibiotic therapy have to be developed to prevent a post-antibiotic catastrophe. This study focuses on the enhancement of Photodynamic Inactivation (PDI) of Gram(+) versus Gram(-) bacteria comparing a cationic derivative of curcumin (SACUR-3) to ...


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