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International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium

Harris, Andrew C. ; Young, Rachel ; Devine, Steven ; Hogan, William J. ; Ayuk, Francis ; Bunworasate, Udomsak ; Chanswangphuwana, Chantiya ; Efebera, Yvonne A. ; Holler, Ernst ; Litzow, Mark ; Ordemann, Rainer ; Qayed, Muna ; Renteria, Anne S. ; Reshef, Ran ; Wölfl, Matthias ; Chen, Yi-Bin ; Goldstein, Steven ; Jagasia, Madan ; Locatelli, Franco ; Mielke, Stephan ; Porter, David ; Schechter, Tal ; Shekhovtsova, Zhanna ; Ferrara, James L. M. ; Levine, John E.



Abstract

Acute graft-versus-host disease (GVHD) remains a leading cause of morbidity and nonrelapse mortality after allogeneic hematopoietic cell transplantation. The clinical staging of GVHD varies greatly between transplant centers and is frequently not agreed on by independent reviewers. The lack of standardized approaches to handle common sources of discrepancy in GVHD grading likely contributes to ...

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