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Vasoactive Therapy in Systemic Sclerosis: Real-life Therapeutic Practice in More Than 3000 Patients

Moinzadeh, Pia ; Riemekasten, Gabriela ; Siegert, Elise ; Fierlbeck, Gerhard ; Henes, Joerg ; Blank, Norbert ; Melchers, Inga ; Mueller-Ladner, Ulf ; Frerix, Marc ; Kreuter, Alexander ; Tigges, Christian ; Lahner, Nina ; Susok, Laura ; Guenther, Claudia ; Zeidler, Gabriele ; Pfeiffer, Christiane ; Worm, Margitta ; Karrer, Sigrid ; Aberer, Elisabeth ; Bretterklieber, Agnes ; Genth, Ekkehard ; Simon, Jan C. ; Distler, Jörg H. W. ; Hein, Ruediger ; Schneider, Matthias ; Seitz, Cornelia S. ; Herink, Claudia ; Steinbrink, Kerstin ; Sárdy, Miklos ; Varga, Rita ; Mensing, Hartwig ; Mensing, Christian ; Lehmann, Percy ; Neeck, Gunther ; Fiehn, Christoph ; Weber, Manfred ; Goebeler, Matthias ; Burkhardt, Harald ; Buslau, Michael ; Ahmadi-Simab, Keihan ; Himsel, Andrea ; Juche, Aaron ; Koetter, Ina ; Kuhn, Annegret ; Sticherling, Michael ; Hellmich, Martin ; Kuhr, Kathrin ; Krieg, Thomas ; Ehrchen, Jan ; Sunderkoetter, Cord ; Hunzelmann, Nicolas



Abstract

Objective. Vasculopathy is a key factor in the pathophysiology of systemic sclerosis (SSc) and the main cause for Raynaud phenomenon (RP), digital ulcers (DU), and/or pulmonary arterial hypertension (PAH). It is so far unknown how patients with SSc are treated with vasoactive agents in daily practice. To determine to which extent patients with SSc were treated with different vasoactive agents, we ...

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