Go to content
UR Home

Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing

Sirianant, Lalida ; Ousingsawat, Jiraporn ; Wanitchakool, Podchanart ; Schreiber, Rainer ; Kunzelmann, Karl


During cell swelling, Cl- channels are activated to lower intracellular Cl- concentrations and to reduce cell volume, a process termed regulatory volume decrease (RVD). We show that anoctamin 6 (ANO6; TMEM16F) produces volume-regulated anion currents and controls cell volume in four unrelated cell types. Volume regulation is compromised in freshly isolated intestinal epithelial cells from Ano6-/- ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons