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Maternal separation facilitates extinction of social fear in adult male mice

Zoicas, Iulia ; Neumann, Inga D.


Early life stress, such as child abuse or neglect, is a risk factor for the development of psychopathologies characterized by abnormal social and emotional behaviors. In rodents, long-lasting changes in stress coping and emotional behavior can be induced by separating pups from their mother. We used maternal separation (MS; 3 h daily on postnatal days 1-14) to test whether early life stress ...


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