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Pre-Analytical Parameters Affecting Vascular Endothelial Growth Factor Measurement in Plasma: Identifying Confounders

Mischak, Harald ; Walz, Johanna M. ; Boehringer, Daniel ; Deissler, Heidrun L. ; Faerber, Lothar ; Goepfert, Jens C. ; Heiduschka, Peter ; Kleeberger, Susannah M. ; Klettner, Alexa ; Krohne, Tim U. ; Schneiderhan-Marra, Nicole ; Ziemssen, Focke ; Stahl, Andreas



Abstract

Background Vascular endothelial growth factor-A (VEGF-A) is intensively investigated in various medical fields. However, comparing VEGF-A measurements is difficult because sample acquisition and pre-analytic procedures differ between studies. We therefore investigated which variables act as confounders of VEGF-A measurements. Methods Following a standardized protocol, blood was taken at three ...

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