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Infiltration of Macrophages Correlates with Severity of Allograft Rejection and Outcome in Human Kidney Transplantation

Chatziantoniou, Christos ; Bergler, Tobias ; Jung, Bettina ; Bourier, Felix ; Kühne, Louisa ; Banas, Miriam C. ; Rümmele, Petra ; Wurm, Simone ; Banas, Bernhard


Objective Despite substantial progress in recent years, graft survival beyond the first year still requires improvement. Since modern immunosuppression addresses mainly T-cell activation and proliferation, we studied macrophage infiltration into the allografts of 103 kidney transplant recipients during acute antibody and T-cell mediated rejection. Macrophage infiltration was correlated with both ...


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