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CE-UV/VIS and CE-MS for monitoring organic impurities during the downstream processing of fermentative-produced lactic acid from second-generation renewable feedstocks

Laube, Hendrik ; Matysik, Frank-Michael ; Schmidberger, Andreas ; Mehlmann, Kerstin ; Toursel, Andreas ; Boden, Jana


Background: During the downstream process of bio-based bulk chemicals, organic impurities, mostly residues from the fermentation process, must be separated to obtain a pure and ready-to-market chemical. In this study, capillary electrophoresis was investigated for the non-targeting downstream process monitoring of organic impurities and simultaneous quantitative detection of lactic acid during ...


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