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Epithelial–mesenchymal transformation markers E-cadherin and survivin predict progression of stage pTa urothelial bladder carcinoma

Breyer, Johannes ; Gierth, Michael ; Shalekenov, Sanzhar ; Aziz, Atiqullah ; Schäfer, Julius ; Burger, Maximilian ; Denzinger, Stefan ; Hofstädter, Ferdinand ; Giedl, Christian ; Otto, Wolfgang


To determine whether the immunohistochemical markers survivin and E-cadherin can predict progress at initially diagnosed Ta bladder cancer. We retrospectively searched for every initially diagnosed pTa urothelial bladder carcinoma having been treated at our single-center hospital in Germany from January 1992 up to December 2004. Follow-up was recorded up to June 2010, with recurrence or progress ...


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