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Existence of circulating anti-endothelial cell antibodies after heart transplantation is associated with post-transplant acute allograft rejection

Lehle, Karla ; Kroher, Johannes ; Kolat, Philipp ; von Süßkind-Schwendi, Marietta ; Schmid, Christof ; Haneya, Assad ; Rupprecht, Leopold ; Hirt, Stephan



Abstract

Anti-endothelial cell antibodies (AECA) may be involved in the development of heart allograft rejection. Its detection might be a cheap and noninvasive method to identify high-risk patients. An indirect immunofluorescence method on human umbilical vein endothelial cells was used to investigate the presence of AECAs in 260 pre- and post-transplant serum samples sequentially collected from 34 ...

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