Abstract
Paraneoplastic rheumatological syndromes in association with haematological malignancies present in a complex clinical setting and may mislead to the diagnosis of an autoimmune disorder. It is of the utmost importance to discover the underlying haematological malignancy. Otherwise a delay in diagnosis might impair treatment options and the prognosis of the patient. Poor response to therapies used ...
Abstract
Paraneoplastic rheumatological syndromes in association with haematological malignancies present in a complex clinical setting and may mislead to the diagnosis of an autoimmune disorder. It is of the utmost importance to discover the underlying haematological malignancy. Otherwise a delay in diagnosis might impair treatment options and the prognosis of the patient. Poor response to therapies used in non-paraneoplastic rheumatic conditions and/or characteristic clinical signs should trigger the rheumatologist to exclude an underlying malignancy. Frequent haematological malignancies as a cause of an autoimmune disorder are lymphomas (Non-Hodgkin lymphoma, Hodgkin lymphoma) and myelodysplastic or myeloproliferative disorders.