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miRNA expression profiling of Epstein-Barr virus-associated NKTL cell lines by Illumina deep sequencing

Alles, Julia ; Menegatti, Jennifer ; Motsch, Natalie ; Hart, Martin ; Eichner, Norbert ; Reinhardt, Richard ; Meister, Gunter ; Grässer, Friedrich A.



Abstract

The aim of this work was to establish the microRNA profile of SNK6 and SNT16, two Epstein-Barr virus (EBV)-infected cell lines derived from nasal NK/T-cell lymphoma (NKTL). The oncogenic EBV is strongly associated with the pathogenesis of nasal and extranodal NK/T-cell lymphoma and expresses 44 mature microRNAs and two noncoding EBV-encoded RNAs (EBERs). miRNAs are 19-25nt noncoding RNAs that ...

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