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Acute Toxicity Grade 3 and 4 After Irradiation in Children and Adolescents: Results From the IPPARCA Collaboration

Pixberg, Caroline ; Koch, Raphael ; Eich, Hans Theodor ; Martinsson, Ulla ; Kristensen, Ingrid ; Matuschek, Christiane ; Kortmann, Rolf-Dieter ; Pohl, Fabian ; Elsayad, Khaled ; Christiansen, Hans ; Willich, Normann ; Lindh, Jack ; Steinmann, Diana


Purpose: In the context of oncologic therapy for children, radiation therapy is frequently indicated. This study identified the frequency of and reasons for the development of high-grade acute toxicity and possible sequelae. Materials and Methods: Irradiated children have been prospectively documented since 2001 in the Registry for the Evaluation of Side Effects After Radiation in Childhood and ...


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