Item type: | Article | ||||
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Journal or Publication Title: | Medizinische Klinik - Intensivmedizin und Notfallmedizin | ||||
Publisher: | Springer | ||||
Place of Publication: | NEW YORK | ||||
Volume: | 111 | ||||
Number of Issue or Book Chapter: | 6 | ||||
Page Range: | pp. 501-507 | ||||
Date: | 2016 | ||||
Institutions: | Medicine > Lehrstuhl für Chirurgie Medicine > Abteilung für Nephrologie Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien | ||||
Identification Number: |
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Keywords: | CRITICALLY-ILL PATIENTS; CYCLE ARREST BIOMARKERS; ACUTE-RENAL-FAILURE; MECHANICAL VENTILATION; OUTCOMES; MULTICENTER; TRIAL; AKI; VALIDATION; THERAPY; Early diagnosis; Health care economics; Myocardial infarction; Acute respiratory distress syndrome; Sepsis | ||||
Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
Status: | Published | ||||
Refereed: | Yes, this version has been refereed | ||||
Created at the University of Regensburg: | Yes | ||||
Item ID: | 42461 |
Abstract
The prognosis of intensive care patients with acute kidney injury (AKI), which is associated with increased mortality is still poor. Current data on the prevalence and the resulting costs of AKI and an overview of the most common diagnoses associated with AKI in German intensive care units (ICU) are lacking. In this retrospective study all adult admissions (> 18 Jahre) in the five ICUs at the ...
Abstract
The prognosis of intensive care patients with acute kidney injury (AKI), which is associated with increased mortality is still poor. Current data on the prevalence and the resulting costs of AKI and an overview of the most common diagnoses associated with AKI in German intensive care units (ICU) are lacking. In this retrospective study all adult admissions (> 18 Jahre) in the five ICUs at the University Clinic Regensburg (in total 78 beds) from1 January 2011 to 31 December 2013 were evaluated. The ICU diagnoses commonly associated with AKI were identified using the international classification of diseases 10 (ICD 10). The length of ICU and hospital stays and AKI-associated hospital costs in the diagnosis-related groups (DRG) based reimbursement system were compared. A total of 891 ICU patients with AKI were classified according to the ICD 10 code. Acute respiratory distress syndrome (ARDS), myocardial infarction (MI) and sepsis were the three most common ICU conditions associated with AKI. A total of 1103 patients were admitted with 1 of these 3 main diagnoses and 249 (22.6 %) of these patients developed AKI. Patients with AKI had significantly longer mean ICU and hospital stays compared to patients without AKI (18.6 vs 5.1 days and 23.8 vs. 10.4 days, respectively, p < 0.001). The presence of AKI in critically ill patients with ARDS, MI and sepsis resulted in additional costs of 2,019,120.42 a,not sign at the University Hospital of Regensburg in 2013. Acute kidney injury in critically ill patients represents a significant medical and socioeconomic burden. Early recognition of patients at risk, coordinated research into novel interventions and establishment of the National Acute Kidney Injury Network for implementation of evidence-based therapies may be the next steps to decrease the incidence and severity of AKI and save costs for the national healthcare system.
Metadata last modified: 17 Feb 2022 09:52