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Depth-dependent changes of obstruction patterns under increasing sedation during drug-induced sedation endoscopy: results of a German monocentric clinical trial

Kellner, Patrick ; Herzog, Beatrice ; Plößl, Sebastian ; Rohrmeier, Christian ; Kühnel, Thomas ; Wanzek, Ramona ; Plontke, Stefan ; Herzog, Michael


Drug-induced sedation endoscopy (DISE) and simulated snoring (SimS) can locate the site of obstruction in patients with sleep-disordered breathing (SDB). There is clinical evidence for a change in collapsibility of the upper airway depending on the depth of sedation. So far, a dose-response relationship between sedation and collapsibility has not been demonstrated. DISE and SimS were performed in ...


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