Go to content
UR Home

Exercise training reverses myocardial dysfunction induced by CaMKIIδCoverexpression by restoring Ca2+homeostasis

Høydal, Morten A. ; Stølen, Tomas O. ; Kettlewell, Sarah ; Maier, Lars S. ; Brown, Joan Heller ; Sowa, Tomas ; Catalucci, Daniele ; Condorelli, Gianluigi ; Kemi, Ole J. ; Smith, Godfrey L. ; Wisløff, Ulrik


Several conditions of heart disease, including heart failure and diabetic cardiomyopathy, are associated with upregulation of cytosolic Ca2+ /calmodulin-dependent protein kinase II (CaMKII delta(C)) activity. In the heart, CaMKII delta(C) isoform targets several proteins involved in intracellular Ca2+ homeostasis. We hypothesized that high-intensity endurance training activates mechanisms that ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons