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Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation

Mohty, M. ; Malard, F. ; Abecassis, M. ; Aerts, E. ; Alaskar, A. S. ; Aljurf, M. ; Arat, M. ; Bader, P. ; Baron, F. ; Bazarbachi, A. ; Blaise, D. ; Ciceri, F. ; Corbacioglu, S. ; Dalle, J.-H. ; Dignan, F. ; Fukuda, T. ; Huynh, A. ; Masszi, T. ; Michallet, M. ; Nagler, A. ; NiChonghaile, M. ; Okamoto, S. ; Pagliuca, A. ; Peters, C. ; Petersen, F. B. ; Richardson, P. G. ; Ruutu, T. ; Savani, B. N. ; Wallhult, E ; Yakoub-Agha, I. ; Duarte, R. F. ; Carreras, E.



Abstract

Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (480%). Therefore, careful ...

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