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Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation

Mohty, M ; Malard, F ; Abecassis, M ; Aerts, E ; Alaskar, A S ; Aljurf, M ; Arat, M ; Bader, P ; Baron, F ; Bazarbachi, A ; Blaise, D ; Ciceri, F ; Corbacioglu, S ; Dalle, J-H ; Dignan, F ; Fukuda, T ; Huynh, A ; Masszi, T ; Michallet, M ; Nagler, A ; NiChonghaile, M ; Okamoto, S ; Pagliuca, A ; Peters, C ; Petersen, F B ; Richardson, P G ; Ruutu, T ; Savani, B N ; Wallhult, E ; Yakoub-Agha, I ; Duarte, R F ; Carreras, E



Abstract

Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (480%). Therefore, careful ...

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