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The adaptor protein alpha-syntrophin regulates adipocyte lipid droplet growth

Eisinger, Kristina ; Rein-Fischboeck, Lisa ; Pohl, Rebekka ; Meier, Elisabeth M. ; Krautbauer, Sabrina ; Buechler, Christa



Abstract

The scaffold protein alpha-syntrophin (SNTA) regulates lipolysis indicating a role in lipid homeostasis. Adipocytes are the main lipid storage cells in the body, and here, the function of SNTA has been analyzed in 3T3-L1 cells. SNTA is expressed in preadipocytes and is induced early during adipogenesis. Knockdown of SNTA in preadipocytes increases their proliferation. Proteins which are induced ...

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