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Relation between Acute GVHD and NK Cell Subset Reconstitution Following Allogeneic Stem Cell Transplantation

Ullrich, Evelyn ; Salzmann-Manrique, Emilia ; Bakhtiar, Shahrzad ; Bremm, Melanie ; Gerstner, Stephanie ; Herrmann, Eva ; Bader, Peter ; Hoffmann, Petra ; Holler, Ernst ; Edinger, Matthias ; Wolff, Daniel



Abstract

One of the major challenges of allogeneic stem cell transplantation (allo-SCT) is to reduce the risk of graft-versus-host disease (GVHD) while boosting the graft-versus-leukemia (GVL) effect. The reconstitution of natural killer (NK) cells following allo-SCT is of notable interest due to their known capability to induce GVL without GVHD. Here, in this study, we investigate the association between ...

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