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The “Intermediate” CD14++CD16+ monocyte subset increases in severe peripheral artery disease in humans

Wildgruber, Moritz ; Aschenbrenner, Teresa ; Wendorff, Heiko ; Czubba, Maria ; Glinzer, Almut ; Haller, Bernhard ; Schiemann, Matthias ; Zimmermann, Alexander ; Berger, Hermann ; Eckstein, Hans-Henning ; Meier, Reinhard ; Wohlgemuth, Walter A. ; Libby, Peter ; Zernecke, Alma



Abstract

Monocytes are key players in atherosclerotic. Human monocytes display a considerable heterogeneity and at least three subsets can be distinguished. While the role of monocyte subset heterogeneity has already been well investigated in coronary artery disease (CAD), the knowledge about monocytes and their heterogeneity in peripheral artery occlusive disease (PAOD) still is limited. Therefore, we ...

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