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Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial

Thomusch, Oliver ; Wiesener, Michael ; Opgenoorth, Mirian ; Pascher, Andreas ; Woitas, Rainer Peter ; Witzke, Oliver ; Jaenigen, Bernd ; Rentsch, Markus ; Wolters, Heiner ; Rath, Thomas ; Cingöz, Tülay ; Benck, Urs ; Banas, Bernhard ; Hugo, Christian


Background Standard practice for immunosuppressive therapy after renal transplantation is quadruple therapy using antibody induction, low-dose tacrolimus, mycophenolate mofetil, and corticosteroids. Long-term steroid intake significantly increases cardiovascular risk factors with negative effects on the outcome, especially post-transplantation diabetes associated with morbidity and mortality. In ...


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