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Cell-protection mechanism through autophagy in HGFs/S. mitis co-culture treated with Chitlac-nAg

Gallorini, Marialucia ; di Giacomo, Viviana ; Di Valerio, Valentina ; Rapino, Monica ; Bosco, Domenico ; Travan, Andrea ; Di Giulio, Mara ; Di Pietro, Roberta ; Paoletti, Sergio ; Cataldi, Amelia ; Sancilio, Silvia


Silver-based products have been proven to be effective in retarding and preventing bacterial growth since ancient times. In the field of restorative dentistry, the use of silver ions/nanoparticles has been explored to counteract bacterial infections, as silver can destroy bacterial cell walls by reacting with membrane proteins. However, it is also cytotoxic towards eukaryotic cells, which are ...


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