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miRNA-101 supports the osteogenic differentiation in human dental follicle cells

Klingelhöffer, Christoph ; Codrin, Consuela ; Ettl, Tobias ; Reichert, Torsten ; Morsczeck, Christian



Abstract

Objective: Human dental follicle cells (DFCs) are genuine precursor cells of cementoblasts and alveolar bone osteoblasts. MicroRNAs (miRNAs) represent a class of non-coding endogenous RNAs that silence gene expression post-transcriptionally. miRNA101 actively regulates the osteogenic differentiation of periodontal ligament cells. Therefore the aim of this study was to investigate the role of ...

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