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Second Cancer Risk after simultaneous integrated boost radiation therapy of right sided breast cancer with and without flattening filter

Dobler, Barbara ; Maier, Johannes ; Knott, Bernadette ; Maerz, Manuel ; Loeschel, Rainer ; Koelbl, Oliver


Background The aim of this study was to investigate if the flattening filter free mode (FFF) of a linear accelerator reduces the excess absolute risk (EAR) for second cancer as compared to the flat beam mode (FF) in simultaneous integrated boost (SIB) radiation therapy of right-sided breast cancer. Patients and methods Six plans were generated treating the whole breast to 50.4 Gy and a SIB volume ...


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