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The extracellular concentration of osteocalcin decreased in dental follicle cell cultures during biomineralization

Klingelhöffer, C. ; Reck, A. ; Morsczeck, C.


The secretion of osteocalcin (OCN) is an excellent differentiation marker for the osteogenic differentiation. This study investigated the secretion of OCN during the osteogenic differentiation of DFCs. During the differentiation of DFCs the extracellular concentrations of OCN were higher in standard cell culture medium than in osteogenic differentiation medium. However, after 4 weeks in the ...


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