Go to content
UR Home

Attenuation of Hypertrophy in Human MSCs via Treatment with a Retinoic Acid Receptor Inverse Agonist

URN to cite this document:
DOI to cite this document:
Riedl, Moritz ; Witzmann, Christina ; Koch, Matthias ; Lang, Siegmund ; Kerschbaum, Maximilian ; Baumann, Florian ; Krutsch, Werner ; Docheva, Denitsa ; Alt, Volker ; Pfeifer, Christian
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 26 Mar 2020 15:18


In vitro chondrogenically differentiated mesenchymal stem cells (MSCs) have a tendency to undergo hypertrophy, mirroring the fate of transient “chondrocytes” in the growth plate. As hypertrophy would result in ossification, this fact limits their use in cartilage tissue engineering applications. During limb development, retinoic acid receptor (RAR) signaling exerts an important influence on cell ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons