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Increased cytoplasmatic expression of cancer immune surveillance receptor CD1d in anaplastic thyroid carcinomas

Weber, Florian ; Junger, Henrik ; Werner, Jens M. ; Velez Char, Natalia ; Rejas, Carolina ; Schlitt, Hans J. ; Hornung, Matthias
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Date of publication of this fulltext: 09 Apr 2020 16:59


Abstract

Background Anaplastic thyroid carcinomas are associated with rapid tumor growth, short survival time and without any promising therapy to improve the poor prognosis. In this study, expression of immunoregulative receptor CD1d and lymphocyte infiltration in different thyroid tumors as well as in healthy tissue were analyzed in order to find new targets for an immunotherapeutic ...

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