Go to content
UR Home

Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A

URN to cite this document:
DOI to cite this document:
Centeio, Raquel ; Cabrita, Inês ; Benedetto, Roberta ; Talbi, Khaoula ; Ousingsawat, Jiraporn ; Schreiber, Rainer ; Sullivan, John K. ; Kunzelmann, Karl
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 12 May 2020 12:33


TMEM16A is a Ca2+ activated Cl- channel with important functions in airways, intestine, and other epithelial organs. Activation of TMEM16A is proposed as a therapy in cystic fibrosis (CF) to reinstall airway Cl- secretion and to enhance airway surface liquid (ASL). This CFTR-agnostic approach is thought to improve mucociliary clearance and lung function in CF. This could indeed improve ASL, ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons