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Effects of Compressive and Tensile Strain on Macrophages during Simulated Orthodontic Tooth Movement

Schröder, Agnes ; Käppler, Paul ; Nazet, Ute ; Jantsch, Jonathan ; Proff, Peter ; Cieplik, Fabian ; Deschner, James ; Kirschneck, Christian
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Date of publication of this fulltext: 13 May 2020 08:05


Abstract

During orthodontic tooth movement (OTM) to therapeutically correct the position of misaligned teeth, thus improving oral health and quality of life, fibroblasts, macrophages, and other immune cells within the periodontal ligament (PDL), which connects a tooth to its surrounding bone, are exposed to compressive and tensile strain. While it is known that PDL fibroblasts are critically involved in ...

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