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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-432217
- DOI to cite this document:
- 10.5283/epub.43221
Abstract
Establishing gene regulatory networks during differentiation or reprogramming requires master or pioneer transcription factors (TFs) such as PU.1, a prototype master TF of hematopoietic lineage differentiation. To systematically determine molecular features that control its activity, here we analyze DNA-binding in vitro and genome-wide in vivo across different cell types with native or ectopic ...

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