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Unusual Late Relapse of ALK-Positive Anaplastic Large Cell Lymphoma Successfully Cleared Using the ALK-Inhibitor Crizotinib: Case Report

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Harrer, Dennis Christoph ; Menhart, Karin ; Mayer, Stephanie ; Herr, Wolfgang ; Reichle, Albrecht ; Vogelhuber, Martin
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 02 Nov 2020 11:57


Anaplastic large cell lymphoma (ALCL) with ALK-translocation constitutes an aggressive lymphoma with high sensitivity to anthracycline-based chemotherapy. Relapse, however, is observed in about one-third of patients. Salvage treatment incorporates high-dose chemotherapy followed by autologous or allogeneic stem cell transplantation, treatment with the CD30-specific immunoconjugate Brentuximab ...


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