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Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD)

URN to cite this document:
urn:nbn:de:bvb:355-epub-440905
DOI to cite this document:
10.5283/epub.44090
Kiel, Christina ; Strunz, Tobias ; Grassmann, Felix ; Weber, Bernhard H. F.
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 13 Jan 2021 12:39



Abstract

Genome-wide association studies (GWAS) have identified an abundance of genetic loci associated with complex traits and diseases. In contrast, in-depth characterization of an individual genetic signal is rarely available. Here, we focus on the genetic variant rs2168518 in 15q24.1 previously associated with age-related macular degeneration (AMD), but only with suggestive evidence. In a two-step ...

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