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Role of Oxygen Supply in Macrophages in a Model of Simulated Orthodontic Tooth Movement

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Schröder, Agnes ; Barschkies, Leonie ; Jantsch, Jonathan ; Proff, Peter ; Gölz, Lina ; Deschner, James ; Kirschneck, Christian
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 12 Nov 2020 13:31


Apart from periodontal ligament fibroblasts, immune cells like macrophages also play an important mediating role in orthodontic tooth movement (OTM). Upon orthodontic force application to malpositioned teeth, macrophages in the periodontal ligament get exposed to both mechanical strain and hypoxic conditions (via a compression of blood vessels). In this study, we assessed the relative impact of ...


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