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Physiological and Pathophysiological Aspects of Primary Cilia—A Literature Review with View on Functional and Structural Relationships in Cartilage

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Barsch, Friedrich ; Niedermair, Tanja ; Mamilos, Andreas ; Schmitt, Volker H. ; Grevenstein, David ; Babel, Maximilian ; Burgoyne, Thomas ; Shoemark, Amelia ; Brochhausen, Christoph
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 Dec 2020 17:24


Cilia are cellular organelles that project from the cell. They occur in nearly all non-hematopoietic tissues and have different functions in different tissues. In mesenchymal tissues primary cilia play a crucial role in the adequate morphogenesis during embryological development. In mature articular cartilage, primary cilia fulfil chemo- and mechanosensitive functions to adapt the cellular ...


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