Go to content
UR Home

Cell-Type-Specific Complement Profiling in the ABCA4−/− Mouse Model of Stargardt Disease

URN to cite this document:
urn:nbn:de:bvb:355-epub-442138
DOI to cite this document:
10.5283/epub.44213
Jabri, Yassin ; Biber, Josef ; Diaz-Lezama, Nundehui ; Grosche, Antje ; Pauly, Diana
[img]
Preview
License: Creative Commons Attribution 4.0
PDF - Published Version
(4MB)
Date of publication of this fulltext: 13 Jan 2021 15:10


Abstract

Stargardt macular degeneration is an inherited retinal disease caused by mutations in the ATP-binding cassette subfamily A member 4 (ABCA4) gene. Here, we characterized the complement expression profile in ABCA4−/− retinae and aligned these findings with morphological markers of retinal degeneration. We found an enhanced retinal pigment epithelium (RPE) autofluorescence, cell loss in the inner ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons