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Lipopolysaccharide Binding Protein and Bactericidal/Permeability-Increasing Protein as Biomarkers for Invasive Pulmonary Aspergillosis

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Bülow, Sigrid ; Heyd, Robert ; Toelge, Martina ; Ederer, Katharina U. ; Schweda, Annette ; Blaas, Stefan H. ; Hamer, Okka W. ; Hiergeist, Andreas ; Wenzel, Jürgen J. ; Gessner, André
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Jan 2021 09:56


Early diagnosis of invasive pulmonary aspergillosis (IPA) is crucial to prevent lethal disease in immunocompromized hosts. So far, lipopolysaccharide binding protein (LBP) and bactericidal/permeability-increasing protein (BPI) levels have not been evaluated as biomarkers for IPA. IL-8, previously introduced as a biomarker for IPA, was also included in this study. Bronchoalveolar lavage fluid ...


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