Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy

URN to cite this document:: urn:nbn:de:bvb:355-epub-443867
DOI to cite this document:: 10.5283/epub.44386

Ho-Xuan, Hung

; Lehmann, Gerhard ; Glazar, Petar ; Gypas, Foivos ; Eichner, Norbert ; Heizler, Kevin ; Schlitt, Hans J.

; Zavolan, Mihaela ; Rajewsky, Nikolaus ; Meister, Gunter

; Hackl, Christina

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Date of publication of this fulltext: 08 Jan 2021 17:14

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Abstract

Simple Summary Colorectal cancer is one of the most frequent types of cancer world-wide, leading to over 500,000 cancer-related deaths each year. Although many primary colorectal cancer patients can be cured by surgery, up to 60% will develop metastases. Chemotherapeutic strategies are well-established, but finally often lead to chemo-resistance and tumor relapse. A specific chemotherapeutic ...