Steatotic Livers Are More Susceptible to Ischemia Reperfusion Damage after Transplantation and Show Increased γδ T Cell Infiltration

URN to cite this document:: urn:nbn:de:bvb:355-epub-444907
DOI to cite this document:: 10.5283/epub.44490

Eggenhofer, Elke ; Groell, Anja ; Junger, Henrik ; Kasi, Amoon ; Kroemer, Alexander ; Geissler, Edward K. ; Schlitt, Hans J.

; Scherer, Marcus N.

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Date of publication of this fulltext: 01 Mar 2021 11:50

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Abstract

Liver transplantation (LTx) is often the only possible therapy for many end-stage liver diseases, but successful long-term transplant outcomes are limited by multiple factors, including ischemia reperfusion injury (IRI). This situation is aggravated by a shortage of transplantable organs, thus encouraging the use of inferior quality organs. Here, we have investigated early hepatic IRI in a ...