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N-acetyl-b-D-glucosaminidase: A potential cardiorenal biomarker with a relevant impact on ICD shock therapies and mortality

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Allgaier, Raphael ; Strack, Christina ; Wallner, Stefan ; Hubauer, Ute ; Uecer, Ekrem ; Lehn, Petra ; Keyser, Andreas ; Luchner, Andreas ; Maier, Lars ; Jungbauer, Carsten
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 26 Jan 2021 16:32

This publication is part of the DEAL contract with Wiley.


Aims Chronic heart failure may lead to chronic kidney disease. Previous studies suggest tubular markers N-acetyl-b-D-glucosaminidase (NAG) and Kidney-injury-molecule-1 (KIM-1) as potential markers for the cardiorenal syndrome (CRS). The prognostic value of NAG and KIM-1 regarding implantable cardioverter defibrillator (ICD) shock therapies is unknown. Methods We included 314 patients with an ICD ...


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