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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-445317
- DOI to cite this document:
- 10.5283/epub.44531
This publication is part of the DEAL contract with Wiley.
Abstract
Head and neck squamous cell carcinoma (HNSCC) is an aggressive and difficult-to-treat cancer entity. Current therapies ultimately aim to activate the mitochondria-controlled (intrinsic) apoptosis pathway, but complex alterations in intracellular signaling cascades and the extracellular microenvironment hamper treatment response. On the one hand, proteins of the BCL-2 family set the threshold for ...

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