European Dermatology Forum guidelines on topical photodynamic therapy 2019 Part 1: treatment delivery and established indications – actinic keratoses, Bowen's disease and basal cell carcinomas

URN to cite this document:

urn:nbn:de:bvb:355-epub-445988 Copy

DOI to cite this document:

10.5283/epub.44598 Copy

Szeimies, R.-M. ; Morton, M. A. ; Basset‐Seguin, N. ; Calzavara‐Pinton, P. ; Gilaberte, Y. ; Hædersdal, M. ; Hofbauer, G. F. L. ; Hunger, R. E. ; Karrer, S. ; Piaserico, S. ; Ulrich, C. ; Wennberg, A.-M. ; Braathen, L. R.

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Date of publication of this fulltext: 26 Jan 2021 18:43

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Details

Item type:	Article
Open Access Type:	DEAL (Wiley)
Journal or Publication Title:	Journal of the European Academy of Dermatology and Venereology
Publisher:	Wiley
Place of Publication:	HOBOKEN
Volume:	33
Number of Issue or Book Chapter:	12
Page Range:	pp. 2225-2238
Date:	December 2019
Institutions:	Medicine > Lehrstuhl für Dermatologie und Venerologie
Identification Number:	Value Type 10.1111/jdv.16017 DOI
Keywords:	NONMELANOMA SKIN-CANCER; FRACTIONAL LASER TREATMENT; CARBON-DIOXIDE LASER; 5-YEAR FOLLOW-UP; METHYL-AMINOLEVULINATE; 5-AMINOLEVULINIC ACID; BF-200 ALA; FLUORESCENCE DIAGNOSIS; SURGICAL EXCISION; DOUBLE-BLIND;
Dewey Decimal Classification:	600 Technology > 610 Medical sciences Medicine
Status:	Published
Refereed:	Unknown
Created at the University of Regensburg:	Partially
Item ID:	44598

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Abstract

Topical photodynamic therapy (PDT) is a widely approved therapy for actinic keratoses, Bowen's disease (squamous cell carcinoma in situ), superficial and certain thin basal cell carcinomas. Recurrence rates when standard treatment protocols are used are typically equivalent to existing therapies, although inferior to surgery for nodular basal cell carcinoma. PDT can be used both as lesional and ...

Abstract

Topical photodynamic therapy (PDT) is a widely approved therapy for actinic keratoses, Bowen's disease (squamous cell carcinoma in situ), superficial and certain thin basal cell carcinomas. Recurrence rates when standard treatment protocols are used are typically equivalent to existing therapies, although inferior to surgery for nodular basal cell carcinoma. PDT can be used both as lesional and field therapies and has the potential to delay/reduce the development of new lesions. A protocol using daylight to treat actinic keratoses is widely practised, with conventional PDT using a red light after typically a 3-h period of occlusion employed for other superficial skin cancer indications as well as for actinic keratoses when daylight therapy is not feasible. PDT is a well-tolerated therapy although discomfort associated with conventional protocol may require pain-reduction measures. PDT using daylight is associated with no or minimal pain and preferred by patient. There is an emerging literature on enhancing conventional PDT protocols or combined PDT with another treatment to increase response rates. This guideline, published over two parts, considers all current approved and emerging indications for the use of topical PDT in dermatology, prepared by the PDT subgroup of the European Dermatology Forum guidelines committee. It presents consensual expert recommendations reflecting current published evidence.

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Metadata last modified: 16 Jan 2025 15:00

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