CCN2/CTGF promotor activity in the developing and adult mouse eye

URN to cite this document:: urn:nbn:de:bvb:355-epub-446444
DOI to cite this document:: 10.5283/epub.44644

Fuchshofer, Rudolf

; Dillinger, Andrea E. ; Kuespert, Sabrina ; Froemel, Franziska ; Tamm, Ernst R.

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Date of publication of this fulltext: 02 Feb 2021 14:57

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Abstract

CCN2/CTGF is a matricellular protein that is known to enhance transforming growth factor-beta signaling and to induce a myofibroblast-like phenotype in a variety of cell types. Here, we investigated Ccn2/Ctgf promotor activity during development and in the adult mouse eye, using CTGF(LacZ/+) mice in which the beta-galactosidase reporter gene LacZ had been inserted into the open reading frame of ...