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CCN2/CTGF promotor activity in the developing and adult mouse eye

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Fuchshofer, Rudolf ; Dillinger, Andrea E. ; Kuespert, Sabrina ; Froemel, Franziska ; Tamm, Ernst R.
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 02 Feb 2021 14:57


CCN2/CTGF is a matricellular protein that is known to enhance transforming growth factor-β signaling and to induce a myofibroblast-like phenotype in a variety of cell types. Here, we investigated Ccn2/Ctgf promotor activity during development and in the adult mouse eye, using CTGFLacZ/+ mice in which the β-galactosidase reporter gene LacZ had been inserted into the open reading frame of ...


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