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CCN2/CTGF promotor activity in the developing and adult mouse eye

URN to cite this document:
urn:nbn:de:bvb:355-epub-446444
DOI to cite this document:
10.5283/epub.44644
Fuchshofer, Rudolf ; Dillinger, Andrea E. ; Kuespert, Sabrina ; Froemel, Franziska ; Tamm, Ernst R.
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 02 Feb 2021 14:57


Abstract

CCN2/CTGF is a matricellular protein that is known to enhance transforming growth factor-β signaling and to induce a myofibroblast-like phenotype in a variety of cell types. Here, we investigated Ccn2/Ctgf promotor activity during development and in the adult mouse eye, using CTGFLacZ/+ mice in which the β-galactosidase reporter gene LacZ had been inserted into the open reading frame of ...

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