We show well-posedness of a diffuse interface model for a two-phase flow of two viscous incompressible fluids with different densities locally in time. The model leads to an inhomogeneous Navier-Stokes/Cahn-Hilliard system with a solenoidal velocity field for the mixture, but a variable density of the fluid mixture in the Navier-Stokes type equation. We prove existence of strong solutions locally in time with the aid of a suitable linearization and a contraction mapping argument. To this end, we show maximal L-2-regularity for the Stokes part of the linearized system and use maximal L-p-regularity for the linearized Cahn-Hilliard system.