Go to content
UR Home

TMEM16A drives renal cyst growth by augmenting Ca2+ signaling in M1 cells

URN to cite this document:
DOI to cite this document:
Kunzelmann, Karl ; Cabrita, Ines ; Buchholz, Björn ; Schreiber, Rainer
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 05 Feb 2021 06:18

This publication is part of the DEAL contract with Springer.


Polycystic kidney disease (PKD) leads to continuous decline of renal function by growth of renal cysts. Enhanced proliferation and transepithelial chloride secretion through cystic fibrosis transmembrane conductance regulator (CFTR) and Ca2+-activated TMEM16A Cl- channels is thought to cause an increase in cyst volume. Recent work shows the pro-proliferative role of the Ca2+ activated Cl- channel ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons