Use of fertility treatments in BRCA1/2 mutation carriers and risk for ovarian and breast cancer: a systematic review

URN to cite this document:: urn:nbn:de:bvb:355-epub-447244
DOI to cite this document:: 10.5283/epub.44724

Ortmann, Olaf ; Huber, D. ; Seitz, S. ; Kast, K. ; Emons, G.

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Date of publication of this fulltext: 05 Feb 2021 08:36

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Abstract

Purpose Mutations in the genesBRCA1andBRCA2represent a significant risk factor for ovarian and breast cancer. With increasing number and success rates, fertility protection and treatment are gaining importance also forBRCA1/2mutation carriers. However, the effect on primary cancer risk and risk for recurrence remains unclear. This review analyses the published data on fertility treatment and risk ...