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Endogenous calcitonin gene-related peptide in cerebrospinal fluid and early quality of life and mental health after good-grade spontaneous subarachnoid hemorrhage – A feasibility series

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Bründl, Elisabeth ; Proescholdt, Martin ; Störr, Eva-Maria ; Schödel, Petra ; Bele, Sylvia ; Höhne, Julius ; Zeman, Florian ; Brawanski, Alexander ; Schebesch, Karl-Michael
License: Creative Commons: Attribution 3.0
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Date of publication of this fulltext: 08 Feb 2021 09:51

This publication is part of the DEAL contract with Springer.


The vasodilatory calcitonin gene-related peptide (CGRP) is excessively released after spontaneous subarachnoid hemorrhage (sSAH) and modulates psycho-behavioral function. In this pilot study, we prospectively analyzed the treatment-specific differences in the secretion of endogenous CGRP into cerebrospinal fluid (CSF) during the acute stage after good-grade sSAH and its impact on self-reported ...


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