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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-448044
- DOI to cite this document:
- 10.5283/epub.44804
This publication is part of the DEAL contract with Springer.
Abstract
Cellular nucleic acid levels are specifically regulated by Argonaute (Ago) proteins. Eukaryotic (e)Ago participates mainly in posttranscriptional regulation of gene expression. In contrast, prokaryotic (p)Ago proteins are involved in defense processes. Our work adds to the understanding of pAgo function and elucidates dynamic aspects of Ago-mediated substrate binding thereby highlighting mechanistic differences between eAgo and pAgo proteins.
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