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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-448065
- DOI to cite this document:
- 10.5283/epub.44806
Abstract
The unfolded protein response (UPR), a cellular stress response pathway, is broadly implicated in disease and resistance to therapy. The molecular mechanisms that drive stress-mediated chemoresistance are, however, only poorly understood. We have employed a multiomics approach to determine UPR-induced gene regulation, revealing the UPR regulon. We further observe metabolic rewiring upon stress ...
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