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RNA and DNA Binding Epitopes of the Cold Shock Protein TmCsp from the Hyperthermophile Thermotoga maritima

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DOI to cite this document:
König, Konstanze von ; Kachel, Norman ; Kalbitzer, Hans Robert ; Kremer, Werner
License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 10 Feb 2021 10:23


Prokaryotic cold shock proteins (CSPs) are considered to play an important role in the transcriptional and translational regulation of gene expression, possibly by acting as transcription anti-terminators and “RNA chaperones”. They bind with high affinity to single-stranded nucleic acids. Here we report the binding epitope of TmCsp from Thermotoga maritima for both single-stranded DNA and RNA, ...


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