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RNA and DNA Binding Epitopes of the Cold Shock Protein TmCsp from the Hyperthermophile Thermotoga maritima

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König, Konstanze von ; Kachel, Norman ; Kalbitzer, Hans Robert ; Kremer, Werner
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 10 Feb 2021 10:23

This publication is part of the DEAL contract with Springer.


Prokaryotic cold shock proteins (CSPs) are considered to play an important role in the transcriptional and translational regulation of gene expression, possibly by acting as transcription anti-terminators and "RNA chaperones". They bind with high affinity to single-stranded nucleic acids. Here we report the binding epitope of TmCsp from Thermotoga maritima for both single-stranded DNA and RNA, ...


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