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Accurate quantification of lipid species affected by isobaric overlap in Fourier-Transform mass spectrometry

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Höring, Marcus ; Ejsing, Christer S. ; Krautbauer, Sabrina ; Ertl, Verena M. ; Burkhardt, Ralph ; Liebisch, Gerhard
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 01 Feb 2022 15:11


Lipidomics data require consideration of ions with near-identical masses, which comprises among others the Type-II isotopic overlap. This overlap occurs in series of lipid species differing only by number of double bonds (DBs) mainly because of the natural abundance of C-13-atoms. High-resolution mass spectrometry, such as Fourier-transform mass spectrometry (FTMS), is capable of resolving ...


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