Accurate quantification of lipid species affected by isobaric overlap in Fourier-Transform mass spectrometry

URN to cite this document:: urn:nbn:de:bvb:355-epub-449211
DOI to cite this document:: 10.5283/epub.44921

Höring, Marcus

; Ejsing, Christer S.

; Krautbauer, Sabrina ; Ertl, Verena M. ; Burkhardt, Ralph

; Liebisch, Gerhard

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Date of publication of this fulltext: 01 Feb 2022 15:11

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Abstract

Lipidomics data require consideration of ions with near-identical masses, which comprises amongst others the Type-II isotopic overlap. This overlap occurs in series of lipid species differing only by number of double bonds (DB) mainly due to the natural abundance of 13C-atoms. High-resolution mass spectrometry, such as Fourier-Transform mass spectrometry (FTMS), is capable of resolving Type-II ...